Action Potential Initiation, Propagation, and Cortical Invasion in the Hyperdirect Pathway during Subthalamic Deep Brain Stimulation

BACKGROUND: High frequency (~130 Hz) deep brain stimulation (DBS) of the subthalamic region is an established clinical therapy for the treatment of late stage Parkinson’s disease (PD). Direct modulation of the hyperdirect pathway, defined as cortical layer V pyramidal neurons that send an axon colla...

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Bibliografiset tiedot
Julkaisussa:Brain Stimul
Päätekijät: Anderson, Ross W., Farokhniaee, AmirAli, Gunalan, Kabilar, Howell, Bryan, McIntyre, Cameron C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109410/
https://ncbi.nlm.nih.gov/pubmed/29779963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brs.2018.05.008
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