PSD-95-nNOS Coupling Regulates Contextual Fear Extinction in the Dorsal CA3

Fear extinction depends on N-methyl-D-aspartate glutamate receptors (NMDARs) and brain-derived neurotrophic factor (BDNF) activation in the limbic system. However, postsynaptic density-95 (PSD-95) and neuronal nitric oxide synthase (nNOS) coupling, the downstream signaling of NMDARs activation, obst...

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Published in:Sci Rep
Main Authors: Cai, Cheng-Yun, Chen, Chen, Zhou, Ying, Han, Zhou, Qin, Cheng, Cao, Bo, Tao, Yan, Bian, Xin-Lan, Lin, Yu-Hui, Chang, Lei, Wu, Hai-Yin, Luo, Chun-Xia, Zhu, Dong-Ya
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109109/
https://ncbi.nlm.nih.gov/pubmed/30143658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30899-4
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