Evaluating Tumor Evolution via Genomic Profiling of Individual Tumor Spheroids in a Malignant Ascites

Epithelial ovarian cancer (EOC) is a silent but mostly lethal gynecologic malignancy. Most patients present with malignant ascites and peritoneal seeding at diagnosis. In the present study, we used a laser-aided isolation technique to investigate the clonal relationship between the primary tumor and...

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Publicado en:Sci Rep
Autores principales: Kim, Sungsik, Kim, Soochi, Kim, Jinhyun, Kim, Boyun, Kim, Se Ik, Kim, Min A., Kwon, Sunghoon, Song, Yong Sang
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109089/
https://ncbi.nlm.nih.gov/pubmed/30143682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31097-y
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