RNAm expression profile of cancer marker genes in HepG2 cells treated with different concentrations of a new indolin-3-one from Pseudomonas aeruginosa

The present study tested the effects of a newly identified indolin-3-one compound (compound 1), produced by Pseudomonas aeruginosa, on HepG2 cells. The MTT assays demonstrated decreased metabolic activities in HepG2 cells treated with compound 1, with dose- and time-dependent intensifying effect, st...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Benicio, Lucas Milanez, Simionato, Ane Stefano, Novello, Cláudio Roberto, Guimarães, Jeconias Rocha, Felicidade, Ingrid, de Oliveira, Admilton Gonçalves, de Mello, João Carlos Palazzo, Mantovani, Mário Sérgio, Chryssafidis, Andreas Lazaros, Andrade, Galdino, de Syllos Colus, Ilce Mara, de Oliveira, Marcelo Tempesta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109079/
https://ncbi.nlm.nih.gov/pubmed/30143666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30893-w
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