Phytochemical study and evaluation of cytotoxicity, mutagenicity, cell cycle kinetics and gene expression of Bauhinia holophylla (Bong.) Steud. in HepG2 cells in vitro

Bauhinia holophylla (Bong.) Steud. (Fabaceae) is a plant used in Brazilian folk medicine to treat diabetes and inflammation. This study evaluated the phytochemical properties, cytotoxic, apoptotic, mutagenic/antimutagenic effects and alterations in gene expression (RNAm) in HepG2 cells treated with...

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Detalhes bibliográficos
Publicado no:Cytotechnology
Main Authors: Ribeiro, Diego Luis, Cilião, Heloísa Lizotti, Specian, Ana Flávia Leal, Serpeloni, Juliana Mara, De Oliveira, Marcelo Tempesta, Varanda, Eliana Aparecida, Vilegas, Wagner, Saldanha, Luiz Leonardo, Martínez-López, Wilner, Dokkedal, Anne Lígia, Cólus, Ilce Mara Syllos
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851965/
https://ncbi.nlm.nih.gov/pubmed/29230630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-017-0173-5
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