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Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module
The SET1/MLL family of histone methyltransferases are conserved in eukaryotes and regulate transcription by catalyzing histone H3K4 mono-, di-, and tri-methylation. These enzymes form a common five-subunit catalytic core, whose assembly is critical for their basal and regulated enzymatic activities...
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| Publicado no: | Cell |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6108940/ https://ncbi.nlm.nih.gov/pubmed/30100181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.06.038 |
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