Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module

The SET1/MLL family of histone methyltransferases are conserved in eukaryotes and regulate transcription by catalyzing histone H3K4 mono-, di-, and tri-methylation. These enzymes form a common five-subunit catalytic core, whose assembly is critical for their basal and regulated enzymatic activities...

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Bibliographic Details
Published in:Cell
Main Authors: Hsu, Peter L., Li, Heng, Lau, Ho-Tak, Leonen, Calvin, Dhall, Abhinav, Ong, Shao-En, Chatterjee, Champak, Zheng, Ning
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108940/
https://ncbi.nlm.nih.gov/pubmed/30100181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.06.038
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