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RGS10 Regulates the Expression of Cyclooxygenase-2 and Tumor Necrosis Factor Alpha through a G Protein–Independent Mechanism

The small regulator of G protein signaling protein RGS10 is a key regulator of neuroinflammation and ovarian cancer cell survival; however, the mechanism for RGS10 function in these cells is unknown and has not been linked to specific G protein pathways. RGS10 is highly enriched in microglia, and lo...

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Vydáno v:Mol Pharmacol
Hlavní autoři: Alqinyah, Mohammed, Almutairi, Faris, Wendimu, Menbere Y., Hooks, Shelley B.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108573/
https://ncbi.nlm.nih.gov/pubmed/30049816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.118.111674
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