Telomeric TERB1-TRF1 interaction is crucial for male meiosis

During meiotic prophase, the meiosis-specific telomere-binding protein TERB1 regulates chromosome movement required for homologous pairing and recombination by interacting with the telomeric shelterin subunit TRF1. Here, we report the crystal structure of the TRF1-binding motif of human TERB1 in com...

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Pubblicato in:Nat Struct Mol Biol
Autori principali: Long, Juanjuan, Huang, Chenhui, Chen, Yanyan, Zhang, Ying, Shi, Shaohua, Wu, Ligang, Liu, Yie, Liu, Chengyu, Wu, Jian, Lei, Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108177/
https://ncbi.nlm.nih.gov/pubmed/29083416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3496
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