All-trans retinoic-acid inhibits heterodimeric bone morphogenetic protein 2/7-stimulated osteoclastogenesis, and resorption activity

BACKGROUND: Bone regenerative heterodimeric bone morphogenetic protein 2/7 (BMP2/7) enhances but all-trans retinoic acid (ATRA) inhibits osteoclastogenesis. However, the effect of ATRA on physiological and/or BMP2/7-induced osteoclastogenesis in still unclear. In this study, we aimed to test the eff...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Bi, Wenjuan, Liu, Yi, Guo, Jing, Lin, Zhen, Liu, Jinsong, Zhou, Miao, Wismeijer, Daniel, Pathak, Janak L., Wu, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107948/
https://ncbi.nlm.nih.gov/pubmed/30159139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-018-0246-y
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