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Effect of polymer charge on functional reconstitution of membrane proteins in polymer nanodiscs

Although there is a growing interest in using polymer lipid-nanodiscs, polymer charge pose limitations for studies on membrane proteins. Here, we demonstrate the functional reconstitution of large soluble-domain containing positively-charged ~57-kDa cytochrome-P450 and negatively-charged ~16-kDa cyt...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Ravula, Thirupathi, Hardin, Nathaniel Z., Bai, Jia, Im, Sang-Choul, Waskell, Lucy, Ramamoorthy, Ayyalusamy
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107395/
https://ncbi.nlm.nih.gov/pubmed/30094448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc04184a
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