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Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2
The trimeric SARS coronavirus (SARS-CoV) surface spike (S) glycoprotein consisting of three S1-S2 heterodimers binds the cellular receptor angiotensin-converting enzyme 2 (ACE2) and mediates fusion of the viral and cellular membranes through a pre- to postfusion conformation transition. Here, we rep...
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| Publicado en: | PLoS Pathog |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6107290/ https://ncbi.nlm.nih.gov/pubmed/30102747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007236 |
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