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An improved method for the isolation and identification of unknown proteins that bind to known DNA sequences by affinity capture and mass spectrometry

Transcription of a gene can be regulated at many different levels. One such fundamental level is interaction between protein and DNA. Protein(s) binds to distinct sites on the DNA, which activate, enhance or repress transcription. Despite being such an important process, very few tools exist to iden...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Murarka, Pooja, Srivastava, Preeti
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107227/
https://ncbi.nlm.nih.gov/pubmed/30138440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202602
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