Cholesterol secosterol aldehyde adduction and aggregation of Cu,Zn-superoxide dismutase: Potential implications in ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by degeneration of upper and lower motor neurons. While the fundamental causes of the disease are still unclear, the accumulation of Cu,Zn-superoxide dismutase (SOD1) immunoreactive aggregates is associated with famili...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Dantas, Lucas S., Chaves-Filho, Adriano B., Coelho, Fernando R., Genaro-Mattos, Thiago C., Tallman, Keri A., Porter, Ned A., Augusto, Ohara, Miyamoto, Sayuri
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6106709/
https://ncbi.nlm.nih.gov/pubmed/30142602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.08.007
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