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Antitrypanosomal 8-Hydroxy-Naphthyridines Are Chelators of Divalent Transition Metals
The lack of information regarding the mechanisms of action (MoA) or specific molecular targets of phenotypically active compounds can prove a barrier to their development as chemotherapeutic agents. Here, we report the results of our orthogonal genetic, molecular, and biochemical studies to determin...
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| Publicado en: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6105827/ https://ncbi.nlm.nih.gov/pubmed/29844044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00235-18 |
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