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Assessing the Essentiality of Leishmania donovani Nitroreductase and Its Role in Nitro Drug Activation
The nitroimidazole fexinidazole has potential as a safe and effective oral drug therapy for the treatment of visceral leishmaniasis. To date, nitroheterocyclics have not been used in the treatment of leishmaniasis, and relatively little is known about their mechanism of action. In African trypanosom...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553740/ https://ncbi.nlm.nih.gov/pubmed/23208716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01788-12 |
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