Colistin Does Not Potentiate Ceftazidime-Avibactam Killing of Carbapenem-Resistant Enterobacteriaceae In Vitro or Suppress Emergence of Ceftazidime-Avibactam Resistance

We tested ceftazidime-avibactam and colistin against 24 carbapenem-resistant Enterobacteriaceae (CRE) isolates by time-kill studies. Ceftazidime-avibactam at 0.25×, 1×, and 4× the MIC was bactericidal against 8%, 21%, and 88% of the isolates, respectively. Colistin (2 μg/ml) was bactericidal against...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Shields, Ryan K., Nguyen, M. Hong, Hao, Binghua, Kline, Ellen G., Clancy, Cornelius J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2018
Konular:
Mechanisms of Resistance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105820/
https://ncbi.nlm.nih.gov/pubmed/29891598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01018-18
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