Identifying Spectra of Activity and Therapeutic Niches for Ceftazidime-Avibactam and Imipenem-Relebactam against Carbapenem-Resistant Enterobacteriaceae

We determined imipenem, imipenem-relebactam, ceftazidime, and ceftazidime-avibactam MICs against 100 CRE isolates that underwent whole-genome sequencing. Klebsiella pneumoniae carbapenemases (KPCs) were the most common carbapenemases. Forty-six isolates carried extended-spectrum β-lactamases (ESBLs)...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Haidar, Ghady, Clancy, Cornelius J., Chen, Liang, Samanta, Palash, Shields, Ryan K., Kreiswirth, Barry N., Nguyen, M. Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571343/
https://ncbi.nlm.nih.gov/pubmed/28630202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00642-17
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