Loss of GCNT2/I-branched glycans enhances melanoma growth and survival

Cancer cells often display altered cell-surface glycans compared to their nontransformed counterparts. However, functional contributions of glycans to cancer initiation and progression remain poorly understood. Here, from expression-based analyses across cancer lineages, we found that melanomas exhi...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Sweeney, Jenna Geddes, Liang, Jennifer, Antonopoulos, Aristotelis, Giovannone, Nicholas, Kang, Shuli, Mondala, Tony S., Head, Steven R., King, Sandra L., Tani, Yoshihiko, Brackett, Danielle, Dell, Anne, Murphy, George F., Haslam, Stuart M., Widlund, Hans R., Dimitroff, Charles J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105653/
https://ncbi.nlm.nih.gov/pubmed/30135430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05795-0
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