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KLF6 and STAT3 co-occupy regulatory DNA and functionally synergize to promote axon growth in CNS neurons

The failure of axon regeneration in the CNS limits recovery from damage and disease. Members of the KLF family of transcription factors can exert both positive and negative effects on axon regeneration, but the underlying mechanisms are unclear. Here we show that forced expression of KLF6 promotes a...

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書目詳細資料
發表在:Sci Rep
Main Authors: Wang, Zimei, Mehra, Vatsal, Simpson, Matthew T., Maunze, Brian, Chakraborty, Advaita, Holan, Lyndsey, Eastwood, Erik, Blackmore, Murray G., Venkatesh, Ishwariya
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105645/
https://ncbi.nlm.nih.gov/pubmed/30135567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31101-5
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