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HDAC5-LSD1 Axis Regulates Antineoplastic Effect of Natural HDAC Inhibitor Sulforaphane in Human Breast Cancer Cells

Our recent studies have shown that crosstalk between histone deacetylase 5 (HDAC5) and lysine-specific demethylase 1 (LSD1) facilitates breast cancer progression. In this work, we demonstrated that regulatory activity at −356 to −100 bp promoter element plays a critical role in governing HDAC5 trans...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Cao, Chunyu, Wu, Hao, Vasilatos, Shauna N., Chandran, Uma, Qin, Ye, Wan, Yong, Oesterreich, Steffi, Davidson, Nancy E., Huang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105499/
https://ncbi.nlm.nih.gov/pubmed/29633255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31419
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