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Can Strain Dependent Inhibition of Cross-Bridge Binding Explain Shifts in Optimum Muscle Length?

Skeletal muscle force is generated by cross-bridge interactions between the overlapping contractile proteins, actin and myosin. The geometry of this overlap gives us the force–length relationship in which maximum isometric force is generated at an intermediate, optimum, length. However, the force–le...

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Bibliografische gegevens
Gepubliceerd in:Integr Comp Biol
Hoofdauteurs: Holt, N C, Williams, C D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104710/
https://ncbi.nlm.nih.gov/pubmed/29873724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/icb/icy050
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