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Synthesis and in vitro and in vivo evaluation of urea-based PSMA inhibitors with increased lipophilicity
BACKGROUND: Several radiolabeled prostate-specific membrane antigen (PSMA) inhibitors based on the lysine-urea-glutamate (KuE) motif as the pharmacophore proved to be suitable tools for PET/SPECT imaging of the PSMA expression in prostate cancer patients. PSMA I&T, a theranostic tracer developed...
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| Publicado no: | EJNMMI Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6104465/ https://ncbi.nlm.nih.gov/pubmed/30136051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-018-0440-2 |
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