DNA Methylation Profiles in Whole Blood of Huntington's Disease Patients

Epigenetic mechanisms, especially DNA methylation, are suggested to play a role in the age-of-onset in Huntington's disease (HD) based on studies on patient brains, and cellular and animal models. Methylation is tissue-specific and it is not clear how HD specific methylation in the brain correl...

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Udgivet i:Front Neurol
Main Authors: Zadel, Maja, Maver, Aleš, Kovanda, Anja, Peterlin, Borut
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Neurology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104454/
https://ncbi.nlm.nih.gov/pubmed/30158895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00655
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