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Stepwise C-Terminal Truncation of Cardiac Troponin T Alters Function at Low and Saturating Ca(2+)
Activation of striated muscle contraction occurs in response to Ca(2+) binding to troponin C. The resulting reorganization of troponin repositions tropomyosin on actin and permits activation of myosin-catalyzed ATP hydrolysis. It now appears that the C-terminal 14 amino acids of cardiac troponin T (...
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| Publicat a: | Biophys J |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6104287/ https://ncbi.nlm.nih.gov/pubmed/30057009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.06.028 |
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