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Rapid Isolation of Extracellular Vesicles from Blood Plasma with Size-Exclusion Chromatography Followed by Mass Spectrometry-Based Proteomic Profiling

The presented procedure allows rapid isolation of extracellular vesicles (EVs) from plasma using size-exclusion chromatography (SEC). Additionally, an approach for reducing the lipid and salt content of the EV isolate in preparation for mass spectrometry (MS)-based proteomic analysis is presented. A...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Kreimer, Simion, Ivanov, Alexander R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104059/
https://ncbi.nlm.nih.gov/pubmed/28828666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7253-1_24
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