Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis

Oligodendrocyte progenitor cells (OPC) undergo asymmetric cell division (ACD) to generate one OPC and one differentiating oligodendrocyte (OL) progeny. Loss of pro-mitotic proteoglycan and OPC marker NG2 in the OL progeny is the earliest immunophenotypic change of unknown mechanism that indicates di...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Daynac, Mathieu, Chouchane, Malek, Collins, Hannah Y., Murphy, Nicole E., Andor, Noemi, Niu, Jianqin, Fancy, Stephen P. J., Stallcup, William B., Petritsch, Claudia K.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104045/
https://ncbi.nlm.nih.gov/pubmed/30131568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05099-3
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