Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis

Oligodendrocyte progenitor cells (OPC) undergo asymmetric cell division (ACD) to generate one OPC and one differentiating oligodendrocyte (OL) progeny. Loss of pro-mitotic proteoglycan and OPC marker NG2 in the OL progeny is the earliest immunophenotypic change of unknown mechanism that indicates di...

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Publicat a:Nat Commun
Autors principals: Daynac, Mathieu, Chouchane, Malek, Collins, Hannah Y., Murphy, Nicole E., Andor, Noemi, Niu, Jianqin, Fancy, Stephen P. J., Stallcup, William B., Petritsch, Claudia K.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104045/
https://ncbi.nlm.nih.gov/pubmed/30131568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05099-3
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