The chromosome 11q13.3 amplification associated lymph node metastasis is driven by miR-548k through modulating tumor microenvironment

BACKGROUND: The prognosis for esophageal squamous cell carcinoma (ESCC) patients with lymph node metastasis (LNM) is still dismal. Elucidation of the LNM associated genomic alteration and underlying molecular mechanisms may provide clinical therapeutic strategies for ESCC treatment. METHODS: Joint a...

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Publicat a:Mol Cancer
Autors principals: Zhang, Weimin, Hong, Ruoxi, Li, Lin, Wang, Yan, Du, Peina, Ou, Yunwei, Zhao, Zitong, Liu, Xuefeng, Xiao, Wenchang, Dong, Dezuo, Wu, Qingnan, Chen, Jie, Song, Yongmei, Zhan, Qimin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103855/
https://ncbi.nlm.nih.gov/pubmed/30131072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0871-4
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