Chemokine-Releasing Nanoparticles for Manipulation of the Lymph Node Microenvironment

Chemokines (CKs) secreted by the host cells into surrounding tissue establish concentration gradients directing the migration of leukocytes. We propose an in vivo CK gradient remodeling approach based on sustained release of CKs by the crosslinked poly(N-isopropylacrylamide) hydrogel open meshwork n...

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Bibliographic Details
Published in:Nanomaterials (Basel)
Main Authors: Popova, Taissia G., Teunis, Allison, Magni, Ruben, Luchini, Alessandra, Espina, Virginia, Liotta, Lance A., Popov, Serguei G.
Format: Artigo
Language:Inglês
Published: MDPI 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394634/
https://ncbi.nlm.nih.gov/pubmed/25878893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano5010298
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