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Deletion of Ezrin in B cells of Lyn-deficient mice downregulates lupus pathology()
Genetic deletion of the Src family tyrosine kinase Lyn in mice recapitulates human systemic lupus erythematosus, characterized by hyperactive B cell antigen receptor (BCR) signaling, splenomegaly, autoantibody generation and glomerulonephritis. However, the molecular regulators of autoimmunity in Ly...
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| Publicado en: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6103798/ https://ncbi.nlm.nih.gov/pubmed/30021765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800168 |
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