An alternative conformation of human TrpRS suggests a role of zinc in activating non-enzymatic function

Tryptophanyl-tRNA synthetase (TrpRS) in vertebrates contains a N-terminal extension in front of the catalytic core. Proteolytic removal of the N-terminal 93 amino acids gives rise to T2-TrpRS, which has potent anti-angiogenic activity mediated through its extracellular interaction with VE-cadherin....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:RNA Biol
Päätekijät: Xu, Xiaoling, Zhou, Huihao, Zhou, Quansheng, Hong, Fei, Vo, My-Nuong, Niu, Wanqiang, Wang, Zhiguo, Xiong, Xiaolin, Nakamura, Kanaha, Wakasugi, Keisuke, Schimmel, Paul, Yang, Xiang-Lei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2017
Aiheet:
Research Paper - Solicited
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103731/
https://ncbi.nlm.nih.gov/pubmed/28910573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1377868
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