A fragment of human TrpRS as a potent antagonist of ocular angiogenesis

Pathological angiogenesis contributes directly to profound loss of vision associated with many diseases of the eye. Recent work suggests that human tyrosyl- and tryptophanyl-tRNA synthetases (TrpRS) link protein synthesis to signal transduction pathways including angiogenesis. In this study, we show...

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Main Authors: Otani, Atsushi, Slike, Bonnie M., Dorrell, Michael I., Hood, John, Kinder, Karen, Ewalt, Karla L., Cheresh, David, Schimmel, Paul, Friedlander, Martin
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2002
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC117535/
https://ncbi.nlm.nih.gov/pubmed/11773625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012601899
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