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ROS is the major player in regulating altered autophagy and lifespan in sin-3 mutants of C. elegans
SIN3, a transcriptional corepressor has been implicated in varied functions both as transcription activator and repressor. Recent studies associated Sin3 with the macroautophagic/autophagic process as a negative regulator of Atg8 and Atg32. Though the role of SIN3 in autophagy is being explored, lit...
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| Udgivet i: | Autophagy |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6103711/ https://ncbi.nlm.nih.gov/pubmed/29912629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1474312 |
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