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Challenges of site-specific selenocysteine incorporation into proteins by Escherichia coli

Selenocysteine (Sec), a rare genetically encoded amino acid with unusual chemical properties, is of great interest for protein engineering. Sec is synthesized on its cognate tRNA (tRNA(Sec)) by the concerted action of several enzymes. While all other aminoacyl-tRNAs are delivered to the ribosome by...

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Publicat a:RNA Biol
Autors principals: Fu, Xian, Söll, Dieter, Sevostyanova, Anastasia
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103685/
https://ncbi.nlm.nih.gov/pubmed/29447106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1440876
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