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Challenges of site-specific selenocysteine incorporation into proteins by Escherichia coli

Selenocysteine (Sec), a rare genetically encoded amino acid with unusual chemical properties, is of great interest for protein engineering. Sec is synthesized on its cognate tRNA (tRNA(Sec)) by the concerted action of several enzymes. While all other aminoacyl-tRNAs are delivered to the ribosome by...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Fu, Xian, Söll, Dieter, Sevostyanova, Anastasia
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103685/
https://ncbi.nlm.nih.gov/pubmed/29447106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1440876
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