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Targeting autophagy for therapy of hyperammonemia
Ammonia is a highly neurotoxic metabolite that is efficiently converted into urea or glutamine. During liver failure due to hepatocellular dysfunction or in inherited deficiencies of urea cycle enzymes, ammonia clearance is impaired resulting in systemic hyperammonemia and hepatic encephalopathy tha...
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| Publicado en: | Autophagy |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6103655/ https://ncbi.nlm.nih.gov/pubmed/30035657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1444312 |
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