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Is there a causal link between intracellular Na elevation and metabolic remodelling in cardiac hypertrophy?

Alterations in excitation–contraction coupling and elevated intracellular sodium (Na(i)) are hallmarks of pathological cardiac remodelling that underline contractile dysfunction. In addition, changes in cardiac metabolism are observed in cardiac hypertrophy and heart failure (HF) that lead to a mism...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Aksentijevic, Dunja, O'Brien, Brett A., Eykyn, Thomas R., Shattock, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103460/
https://ncbi.nlm.nih.gov/pubmed/29970448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20170508
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