Expression of oxidized protein tyrosine phosphatase and γH2AX predicts poor survival of gastric carcinoma patients

BACKGROUND: Oxidative stress induces various intracellular damage, which might be correlated with tumorigenesis. Accumulated oxidative stresses might inactivate protein tyrosine phosphatase (PTP) by oxidizing it, and inducing the phosphorylation of H2AX (γH2AX) in response to DNA damage. METHODS: We...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Hussein, Usama Khamis, Park, Ho Sung, Bae, Jun Sang, Kim, Kyoung Min, Chong, Yun Jo, Kim, Chan Young, Kwon, Keun Sang, Chung, Myoung Ja, Lee, Ho, Kang, Myoung Jae, Moon, Woo Sung, Jang, Kyu Yun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102926/
https://ncbi.nlm.nih.gov/pubmed/30126387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4752-4
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