Individual and Combined Expression of DNA Damage Response Molecules PARP1, γH2AX, BRCA1, and BRCA2 Predict Shorter Survival of Soft Tissue Sarcoma Patients

DNA damage response (DDR) molecules are protective against genotoxic stresses. DDR molecules are also involved in the survival of cancer cells in patients undergoing anti-cancer therapies. Therefore, DDR molecules are potential markers of cancer progression in addition to being potential therapeutic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Kyoung Min, Moon, Young Jae, Park, See-Hyoung, Park, Hye Jeong, Wang, Sung Il, Park, Ho Sung, Lee, Ho, Kwon, Keun Sang, Moon, Woo Sung, Lee, Dong Geun, Kim, Jung Ryul, Jang, Kyu Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028069/
https://ncbi.nlm.nih.gov/pubmed/27643881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163193
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