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TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway

BACKGROUND: An acute and drastic inflammatory response characterized by the production of inflammatory mediators is followed by stroke, including SAH. Overactivation of microglia parallels an excessive inflammatory response and worsened brain damage. Previous studies indicate that TSG-6 has potent i...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Li, Ran, Liu, Wenchao, Yin, Jian, Chen, Yunchang, Guo, Shenquan, Fan, Haiyan, Li, Xifeng, Zhang, Xin, He, Xuying, Duan, Chuanzhi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102893/
https://ncbi.nlm.nih.gov/pubmed/30126439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1279-1
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