Tim-3 deteriorates neuroinflammatory and neurocyte apoptosis after subarachnoid hemorrhage through the Nrf2/HMGB1 signaling pathway in rats

Inflammation is known to play an important role in early brain injury (EBI) after subarachnoid hemorrhage (SAH). T cell immunoglobulin and mucin domain-3 (Tim-3) has emerged as a critical regulator of adaptive and innate immune responses, and has been identified to play a vital role in certain infla...

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Bibliographic Details
Published in:Aging (Albany NY)
Main Authors: Guo, Shenquan, Li, Yuanzhi, Wei, Boyang, Liu, Wenchao, Li, Ran, Cheng, Wenping, Zhang, Xin, He, Xuying, Li, Xifeng, Duan, Chuanzhi
Format: Artigo
Language:Inglês
Published: Impact Journals 2020
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695377/
https://ncbi.nlm.nih.gov/pubmed/33168786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103796
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