PU.1 regulates Alzheimer’s disease-associated genes in primary human microglia

BACKGROUND: Microglia play critical roles in the brain during homeostasis and pathological conditions. Understanding the molecular events underpinning microglial functions and activation states will further enable us to target these cells for the treatment of neurological disorders. The transcriptio...

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Bibliografiske detaljer
Udgivet i:Mol Neurodegener
Main Authors: Rustenhoven, Justin, Smith, Amy M., Smyth, Leon C., Jansson, Deidre, Scotter, Emma L., Swanson, Molly E. V., Aalderink, Miranda, Coppieters, Natacha, Narayan, Pritika, Handley, Renee, Overall, Chris, Park, Thomas I. H., Schweder, Patrick, Heppner, Peter, Curtis, Maurice A., Faull, Richard L. M., Dragunow, Mike
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102813/
https://ncbi.nlm.nih.gov/pubmed/30124174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0277-1
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