PU.1 regulates Alzheimer’s disease-associated genes in primary human microglia

BACKGROUND: Microglia play critical roles in the brain during homeostasis and pathological conditions. Understanding the molecular events underpinning microglial functions and activation states will further enable us to target these cells for the treatment of neurological disorders. The transcriptio...

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Détails bibliographiques
Publié dans:Mol Neurodegener
Auteurs principaux: Rustenhoven, Justin, Smith, Amy M., Smyth, Leon C., Jansson, Deidre, Scotter, Emma L., Swanson, Molly E. V., Aalderink, Miranda, Coppieters, Natacha, Narayan, Pritika, Handley, Renee, Overall, Chris, Park, Thomas I. H., Schweder, Patrick, Heppner, Peter, Curtis, Maurice A., Faull, Richard L. M., Dragunow, Mike
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102813/
https://ncbi.nlm.nih.gov/pubmed/30124174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0277-1
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