NPM1 alternative transcripts are upregulated in acute myeloid and lymphoblastic leukemia and their expression level affects patient outcome

BACKGROUND: Expression of the NPM1 gene, encoding nucleophosmin, is upregulated in cancers. Although more than ten NPM1 transcripts are known, the reports were usually limited to one predominant transcript. In leukemia, the NPM1 expression has not been widely studied so far. In acute myeloid leukemi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Transl Med
Hauptverfasser: Handschuh, Luiza, Wojciechowski, Pawel, Kazmierczak, Maciej, Marcinkowska-Swojak, Malgorzata, Luczak, Magdalena, Lewandowski, Krzysztof, Komarnicki, Mieczyslaw, Blazewicz, Jacek, Figlerowicz, Marek, Kozlowski, Piotr
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102803/
https://ncbi.nlm.nih.gov/pubmed/30126426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1608-2
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge