NPM1 alternative transcripts are upregulated in acute myeloid and lymphoblastic leukemia and their expression level affects patient outcome

BACKGROUND: Expression of the NPM1 gene, encoding nucleophosmin, is upregulated in cancers. Although more than ten NPM1 transcripts are known, the reports were usually limited to one predominant transcript. In leukemia, the NPM1 expression has not been widely studied so far. In acute myeloid leukemi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Transl Med
Prif Awduron: Handschuh, Luiza, Wojciechowski, Pawel, Kazmierczak, Maciej, Marcinkowska-Swojak, Malgorzata, Luczak, Magdalena, Lewandowski, Krzysztof, Komarnicki, Mieczyslaw, Blazewicz, Jacek, Figlerowicz, Marek, Kozlowski, Piotr
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102803/
https://ncbi.nlm.nih.gov/pubmed/30126426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1608-2
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