Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory

Aging is accompanied by impairments in both circadian rhythmicity and long-term memory. Although it is clear that memory performance is affected by circadian cycling, it is unknown whether age-related disruption of the circadian clock causes impaired hippocampal memory. Here, we show that the repres...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Kwapis, Janine L., Alaghband, Yasaman, Kramár, Enikö A., López, Alberto J., Vogel Ciernia, Annie, White, André O., Shu, Guanhua, Rhee, Diane, Michael, Christina M., Montellier, Emilie, Liu, Yu, Magnan, Christophe N., Chen, Siwei, Sassone-Corsi, Paolo, Baldi, Pierre, Matheos, Dina P., Wood, Marcelo A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102273/
https://ncbi.nlm.nih.gov/pubmed/30127461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05868-0
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