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Two-step senescence-focused cancer therapies
Damaged cells at risk for neoplastic transformation can be neutralized by apoptosis or engagement of the senescence program, which induces a permanent cell-cycle arrest and a bioactive secretome implicated in tumor immunosurveillance. While from an evolutionary perspective senescence is beneficial i...
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| Publicado no: | Trends Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6102047/ https://ncbi.nlm.nih.gov/pubmed/29776716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2018.04.006 |
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