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Autophagy-dependent ribosomal RNA degradation is essential for maintaining nucleotide homeostasis during C. elegans development

Ribosome degradation through the autophagy-lysosome pathway is crucial for cell survival during nutrient starvation, but whether it occurs under normal growth conditions and contributes to animal physiology remains unaddressed. In this study, we identified RNST-2, a C. elegans T2 family endoribonucl...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Liu, Yubing, Zou, Wei, Yang, Peiguo, Wang, Li, Ma, Yan, Zhang, Hong, Wang, Xiaochen
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101943/
https://ncbi.nlm.nih.gov/pubmed/30102152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36588
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