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Autophagy-dependent ribosomal RNA degradation is essential for maintaining nucleotide homeostasis during C. elegans development

Ribosome degradation through the autophagy-lysosome pathway is crucial for cell survival during nutrient starvation, but whether it occurs under normal growth conditions and contributes to animal physiology remains unaddressed. In this study, we identified RNST-2, a C. elegans T2 family endoribonucl...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Liu, Yubing, Zou, Wei, Yang, Peiguo, Wang, Li, Ma, Yan, Zhang, Hong, Wang, Xiaochen
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101943/
https://ncbi.nlm.nih.gov/pubmed/30102152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36588
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