Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration

Vacuole membrane protein 1 (VMP1), the endoplasmic reticulum (ER)-localized autophagy protein, plays a key role during the autophagy process in mammalian cells. To study the impact of VMP1-deficiency on midbrain dopaminergic (mDAergic) neurons, we selectively deleted VMP1 in the mDAergic neurons of...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Dis
Egile Nagusiak: Wang, Panpan, Chen, Xi, Wang, Yuanyuan, Jia, Congcong, Liu, Xinyao, Wang, Ying, Wu, Haifeng, Cai, Huaibin, Shen, Han-Ming, Le, Weidong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822891/
https://ncbi.nlm.nih.gov/pubmed/33483473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03412-5
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