Dissecting Multi-protein Signaling Complexes by Bimolecular Complementation Affinity Purification (BiCAP)

The assembly of protein complexes is a central mechanism underlying the regulation of many cell signaling pathways. A major focus of biomedical research is deciphering how these dynamic protein complexes act to integrate signals from multiple sources in order to direct a specific biological response...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Hastings, Jordan F., Han, Jeremy Z.R., Shearer, Robert F., Kennedy, Sean P., Iconomou, Mary, Saunders, Darren N., Croucher, David R.
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2018
Fag:
Immunology and Infection
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101743/
https://ncbi.nlm.nih.gov/pubmed/29985350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57109
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