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Semi-quantitative Detection of RNA-dependent RNA Polymerase Activity of Human Telomerase Reverse Transcriptase Protein

Human telomerase reverse transcriptase (TERT) is the catalytic subunit of telomerase, and it elongates telomere through RNA-dependent DNA polymerase activity. Although TERT is named as a reverse transcriptase, structural and phylogenetic analyses of TERT demonstrate that TERT is a member of right-ha...

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Publicado en:J Vis Exp
Autores principales: Maida, Yoshiko, Yasukawa, Mami, Ghilotti, Marco, Ando, Yoshinari, Masutomi, Kenkichi
Formato: Artigo
Lenguaje:Inglês
Publicado: MyJove Corporation 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101702/
https://ncbi.nlm.nih.gov/pubmed/29985366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57021
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