CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma

Neurofibromin 1 (NF1), a tumor suppressor that negatively regulates RAS through its GTPase activity, is highly mutated in various types of sporadic human cancers, including melanoma. However, the binding partners of NF1 and the pathways in which it is involved in melanoma have not been characterized...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Alon, Michal, Arafeh, Rand, Lee, Joo Sang, Madan, Sanna, Kalaora, Shelly, Nagler, Adi, Abgarian, Tereza, Greenberg, Polina, Ruppin, Eytan, Samuels, Yardena
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101293/
https://ncbi.nlm.nih.gov/pubmed/30131853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25805
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